The V‐ATPase is expressed in the choroid plexus and mediates cAMP‐induced intracellular pH alterations

The cerebrospinal fluid (CSF) pH influences brain interstitial pH and, therefore, brain function. We hypothesized that the choroid plexus epithelium (CPE) expresses the vacuolar H(+)‐ATPase (V‐ATPase) as an acid extrusion mechanism in the luminal membrane to counteract detrimental elevations in CSF...

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Bibliografische gegevens
Gepubliceerd in:Physiol Rep
Hoofdauteurs: Christensen, Henriette L., Păunescu, Teodor G., Matchkov, Vladimir, Barbuskaite, Dagne, Brown, Dennis, Damkier, Helle H., Praetorius, Jeppe
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: John Wiley and Sons Inc. 2017
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Original Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5256157/
https://ncbi.nlm.nih.gov/pubmed/28053225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.13072
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