Mutations in the bovine leukemia virus Tax protein can abrogate the long terminal repeat-directed transactivating activity without concomitant loss of transforming potential.

The bovine leukemia virus Tax protein transactivates gene expression directed by the viral long terminal repeat (LTR) and contributes to immortalization of primary cells. Theoretical analysis of the protein sequence revealed the presence of a putative zinc finger structure at its amino end. Selected...

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Main Authors: Willems, L, Grimonpont, C, Heremans, H, Rebeyrotte, N, Chen, G, Portetelle, D, Burny, A, Kettmann, R
Format: Artigo
Sprog:Inglês
Udgivet: 1992
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC525610/
https://ncbi.nlm.nih.gov/pubmed/1315045
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