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Malignant epithelial cells in primary human lung carcinomas coexpress in vivo platelet-derived growth factor (PDGF) and PDGF receptor mRNAs and their protein products.

Lung cancer represents one of the major human carcinomas with the highest degree of mortality. Epidemiologic studies have linked this disease to "chronic injury," largely induced by cigarette smoking. In the present studies, we demonstrate the in vivo expression of platelet-derived growth factor (PD...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Antoniades, H N, Galanopoulos, T, Neville-Golden, J, O'Hara, C J
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 1992
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On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC525607/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1315044/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.9.3942
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