Activation of EVI1 gene expression in human acute myelogenous leukemias by translocations spanning 300-400 kilobases on chromosome band 3q26.

Retroviral activation of Evi-1 gene expression is one of the most common transforming events in murine myeloid leukemias. To evaluate the role of the EVI1 gene in human acute myelogenous leukemia (AML), leukemic blasts or cell lines from 116 patients were examined. In eight patients the EVI1 gene wa...

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Detalhes bibliográficos
Main Authors: Morishita, K, Parganas, E, William, C L, Whittaker, M H, Drabkin, H, Oval, J, Taetle, R, Valentine, M B, Ihle, J N
Formato: Artigo
Idioma:Inglês
Publicado em: 1992
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC525606/
https://ncbi.nlm.nih.gov/pubmed/1570317
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