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Natural antibodies to factor VIII (anti-hemophilic factor) in healthy individuals.

Spontaneous inhibitors of factor VIII (FVIII) are pathogenic IgG autoantibodies of restricted isotypic heterogeneity found in the plasma of patients presenting with bleeding episodes and low levels of FVIII. We now report the presence of a natural FVIII-neutralizing activity in 85 of 500 plasma samp...

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Détails bibliographiques
Auteurs principaux: Algiman, M, Dietrich, G, Nydegger, U E, Boieldieu, D, Sultan, Y, Kazatchkine, M D
Format: Artigo
Langue:Inglês
Publié: 1992
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC525577/
https://ncbi.nlm.nih.gov/pubmed/1570298
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