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Natural antibodies to factor VIII (anti-hemophilic factor) in healthy individuals.
Spontaneous inhibitors of factor VIII (FVIII) are pathogenic IgG autoantibodies of restricted isotypic heterogeneity found in the plasma of patients presenting with bleeding episodes and low levels of FVIII. We now report the presence of a natural FVIII-neutralizing activity in 85 of 500 plasma samp...
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| Udgivet i: | Proc Natl Acad Sci U S A |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
1992
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC525577/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1570298/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.9.3795 |
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