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Natural antibodies to factor VIII (anti-hemophilic factor) in healthy individuals.

Spontaneous inhibitors of factor VIII (FVIII) are pathogenic IgG autoantibodies of restricted isotypic heterogeneity found in the plasma of patients presenting with bleeding episodes and low levels of FVIII. We now report the presence of a natural FVIII-neutralizing activity in 85 of 500 plasma samp...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Proc Natl Acad Sci U S A
Main Authors: Algiman, M, Dietrich, G, Nydegger, U E, Boieldieu, D, Sultan, Y, Kazatchkine, M D
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 1992
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC525577/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1570298/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.9.3795
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