Cyclosporin-mediated inhibition of bovine calcineurin by cyclophilins A and B.

The Ca(2+)- and calmodulin-dependent protein phosphatase calcineurin is inhibited by the immunosuppressant drug cyclosporin A in the presence of cyclophilin A or B. Of the two isoforms, cyclophilin B is more potent by a factor of 2-5 when either the phosphoprotein [32P]casein or the [32P]phosphoseri...

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Hlavní autoři: Swanson, S K, Born, T, Zydowsky, L D, Cho, H, Chang, H Y, Walsh, C T, Rusnak, F
Médium: Artigo
Jazyk:Inglês
Vydáno: 1992
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC525566/
https://ncbi.nlm.nih.gov/pubmed/1315036
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