Regulated expression of the GAL4 activator gene in yeast provides a sensitive genetic switch for glucose repression.
Glucose (catabolite) repression is mediated by multiple mechanisms that combine to regulate transcription of the GAL genes over at least a thousandfold range. We have determined that this is due predominantly to modest glucose repression (4- to 7-fold) of expression of GAL4, the gene encoding the tr...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1991
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC52556/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1924319/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.19.8597 |
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