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Excessive activation of ionotropic glutamate receptors induces apoptotic hair-cell death independent of afferent and efferent innervation

Accumulation of excess glutamate plays a central role in eliciting the pathological events that follow intensely loud noise exposures and ischemia-reperfusion injury. Glutamate excitotoxicity has been characterized in cochlear nerve terminals, but much less is known about whether excess glutamate si...

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Vydáno v:Sci Rep
Hlavní autor: Sheets, Lavinia
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5255535/
https://ncbi.nlm.nih.gov/pubmed/28112265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep41102
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