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Inducible Gene Trapping with Drug-Selectable Markers and Cre/loxP To Identify Developmentally Regulated Genes

Gene trapping in mouse embryonic stem cells is an important genetic approach that allows simultaneous mutation of genes and generation of corresponding mutant mice. We designed a selection scheme with drug selection markers and Cre/loxP technology which allows screening of gene trap events that resp...

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Detalhes bibliográficos
Main Authors: Chen, You-Tzung, Liu, Pentao, Bradley, Allan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC525470/
https://ncbi.nlm.nih.gov/pubmed/15509795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.22.9930-9941.2004
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