Decreased Bioavailability of Rifampin and Other Antituberculosis Drugs in Patients with Advanced Human Immunodeficiency Virus Disease

We evaluated the effects of human immunodeficiency virus (HIV) disease on pharmacokinetics of antituberculosis medications by measuring concentrations of isoniazid and rifampin in blood and of pyrazinamide and ethambutol in urine. Peak concentration and exposure were reduced for rifampin, and rapid...

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Hlavní autoři: Gurumurthy, Prema, Ramachandran, Geetha, Hemanth Kumar, A. K., Rajasekaran, S., Padmapriyadarsini, C., Swaminathan, Soumya, Bhagavathy, S., Venkatesan, P., Sekar, L., Mahilmaran, A., Ravichandran, N., Paramesh, P.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2004
Témata:
Pharmacology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC525439/
https://ncbi.nlm.nih.gov/pubmed/15504887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.11.4473-4475.2004
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