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Nevirapine Significantly Reduces the Levels of Racemic Methadone and (R)-Methadone in Human Immunodeficiency Virus-Infected Patients

Methadone is metabolized by various isoforms of the cytochrome P450 family, which can be induced by many drugs, including nevirapine. The objective of the present study was to determine the effects of coadministration of nevirapine and methadone on the dose-adjusted areas under the concentration-tim...

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Autori principali: Stocker, Hartmut, Kruse, Guido, Kreckel, Peter, Herzmann, Christian, Arastéh, Keikawus, Claus, Jörg, Jessen, Heiko, Cordes, Christiane, Hintsche, Bettina, Schlote, Frank, Schneider, Lothar, Kurowski, Michael
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2004
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC525438/
https://ncbi.nlm.nih.gov/pubmed/15504834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.11.4148-4153.2004
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