Nevirapine Significantly Reduces the Levels of Racemic Methadone and (R)-Methadone in Human Immunodeficiency Virus-Infected Patients

Methadone is metabolized by various isoforms of the cytochrome P450 family, which can be induced by many drugs, including nevirapine. The objective of the present study was to determine the effects of coadministration of nevirapine and methadone on the dose-adjusted areas under the concentration-tim...

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Detalhes bibliográficos
Main Authors: Stocker, Hartmut, Kruse, Guido, Kreckel, Peter, Herzmann, Christian, Arastéh, Keikawus, Claus, Jörg, Jessen, Heiko, Cordes, Christiane, Hintsche, Bettina, Schlote, Frank, Schneider, Lothar, Kurowski, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC525438/
https://ncbi.nlm.nih.gov/pubmed/15504834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.11.4148-4153.2004
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