Quinolone-Resistant Haemophilus influenzae: Determination of Mutant Selection Window for Ciprofloxacin, Garenoxacin, Levofloxacin, and Moxifloxacin

Stepwise selection of ciprofloxacin-resistant Haemophilus influenzae mutants produced first-, second-, third-, and fourth-step substitutions in GyrA (S84Y), ParC (S84R), GyrA (D88N), and ParC (E88K), respectively. Successive mutations raised the mutant selection window. The wild-type selection windo...

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Autores principales: Li, Xinying, Mariano, Noriel, Rahal, James J., Urban, Carl M., Drlica, Karl
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2004
Materias:
Mechanisms of Resistance
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC525419/
https://ncbi.nlm.nih.gov/pubmed/15504883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.11.4460-4462.2004
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