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PSSV: a novel pattern-based probabilistic approach for somatic structural variation identification

Motivation: Whole genome DNA-sequencing (WGS) of paired tumor and normal samples has enabled the identification of somatic DNA changes in an unprecedented detail. Large-scale identification of somatic structural variations (SVs) for a specific cancer type will deepen our understanding of driver mech...

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Publicat a:Bioinformatics
Autors principals: Chen, Xi, Shi, Xu, Hilakivi-Clarke, Leena, Shajahan-Haq, Ayesha N., Clarke, Robert, Xuan, Jianhua
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5254081/
https://ncbi.nlm.nih.gov/pubmed/27659451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btw605
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