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Improved methods for multi-trait fine mapping of pleiotropic risk loci

Motivation: Genome-wide association studies (GWAS) have identified thousands of regions in the genome that contain genetic variants that increase risk for complex traits and diseases. However, the variants uncovered in GWAS are typically not biologically causal, but rather, correlated to the true ca...

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Detalhes bibliográficos
Publicado no:Bioinformatics
Main Authors: Kichaev, Gleb, Roytman, Megan, Johnson, Ruth, Eskin, Eleazar, Lindström, Sara, Kraft, Peter, Pasaniuc, Bogdan
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5254076/
https://ncbi.nlm.nih.gov/pubmed/27663501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btw615
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