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Expression of the novel maternal centrosome assembly factor Wdr8 is required for vertebrate embryonic mitoses

The assembly of the first centrosome occurs upon fertilisation when male centrioles recruit pericentriolar material (PCM) from the egg cytoplasm. The mechanisms underlying the proper assembly of centrosomes during early embryogenesis remain obscure. We identify Wdr8 as a novel maternally essential p...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Inoue, Daigo, Stemmer, Manuel, Thumberger, Thomas, Ruppert, Thomas, Bärenz, Felix, Wittbrodt, Joachim, Gruss, Oliver J.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5253655/
https://ncbi.nlm.nih.gov/pubmed/28098238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms14090
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