Exome and genome sequencing of nasopharynx cancer identifies NF-κB pathway activating mutations

Nasopharyngeal carcinoma (NPC) is an aggressive head and neck cancer characterized by Epstein-Barr virus (EBV) infection and dense lymphocyte infiltration. The scarcity of NPC genomic data hinders the understanding of NPC biology, disease progression and rational therapy design. Here we performed wh...

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Publicado no:Nat Commun
Main Authors: Li, Yvonne Y, Chung, Grace T. Y., Lui, Vivian W. Y., To, Ka-Fai, Ma, Brigette B. Y., Chow, Chit, Woo, John K, S., Yip, Kevin Y., Seo, Jeongsun, Hui, Edwin P., Mak, Michael K. F., Rusan, Maria, Chau, Nicole G., Or, Yvonne Y. Y., Law, Marcus H. N., Law, Peggy P. Y., Liu, Zoey W. Y., Ngan, Hoi-Lam, Hau, Pok-Man, Verhoeft, Krista R., Poon, Peony H. Y., Yoo, Seong-Keun, Shin, Jong-Yeon, Lee, Sau-Dan, Lun, Samantha W. M., Jia, Lin, Chan, Anthony W. H., Chan, Jason Y. K., Lai, Paul B. S., Fung, Choi-Yi, Hung, Suet-Ting, Wang, Lin, Chang, Ann Margaret V., Chiosea, Simion I., Hedberg, Matthew L., Tsao, Sai-Wah, van Hasselt, Andrew C., Chan, Anthony T. C., Grandis, Jennifer R., Hammerman, Peter S., Lo, Kwok-Wai
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5253631/
https://ncbi.nlm.nih.gov/pubmed/28098136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms14121
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