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Soft matrices downregulate FAK activity to promote growth of tumor-repopulating cells
Tumor-repopulating cells are a tumorigenic sub-population of cancer cells that drives tumorigenesis. We have recently reported that soft fibrin matrices maintain tumor-repopulating cell growth by promoting histone 3 lysine 9 (H3K9) demethylation and Sox2 expression and that Cdc42 expression influenc...
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| Publicado en: | Biochem Biophys Res Commun |
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| Main Authors: | , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2016
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5253317/ https://ncbi.nlm.nih.gov/pubmed/28007596 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2016.12.122 |
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