Soft matrices downregulate FAK activity to promote growth of tumor-repopulating cells

Tumor-repopulating cells are a tumorigenic sub-population of cancer cells that drives tumorigenesis. We have recently reported that soft fibrin matrices maintain tumor-repopulating cell growth by promoting histone 3 lysine 9 (H3K9) demethylation and Sox2 expression and that Cdc42 expression influenc...

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Publicado en:Biochem Biophys Res Commun
Main Authors: Tan, Youhua, Wood, Adam Richard, Jia, Qiong, Zhou, Wenwen, Luo, Junyu, Yang, Fang, Chen, Junwei, Chen, Junjian, Sun, Jian, Seong, Jihye, Tajik, Arash, Singh, Rishi, Wang, Ning
Formato: Artigo
Idioma:Inglês
Publicado: 2016
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5253317/
https://ncbi.nlm.nih.gov/pubmed/28007596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2016.12.122
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