Generation of organized germ layers from a single mouse embryonic stem cell

Mammalian inner cell mass cells undergo lineage-specific differentiation into germ layers of endoderm, mesoderm and ectoderm during gastrulation. It has been a long-standing challenge in developmental biology to replicate these organized germ layer patterns in culture. Here we present a method of ge...

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Autors principals: Poh, Yeh-Chuin, Chen, Junwei, Hong, Ying, Yi, Haiying, Zhang, Shuang, Chen, Junjian, Wu, Douglas C., Wang, Lili, Jia, Qiong, Singh, Rishi, Yao, Wenting, Tan, Youhua, Tajik, Arash, Tanaka, Tetsuya S., Wang, Ning
Format: Artigo
Idioma:Inglês
Publicat: Nature Pub. Group 2014
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4050279/
https://ncbi.nlm.nih.gov/pubmed/24873804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms5000
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