Interleukin 1 is processed and released during apoptosis.

Interleukin (IL-) 1 alpha and 1 beta are synthesized as 31- to 34-kDa pro molecules. They are released from monocytes and macrophages as proteolytically processed 17-kDa mature molecules that bind with high affinity to specific receptors on target cells. IL-1 is not released via the classic secretor...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Hogquist, K A, Nett, M A, Unanue, E R, Chaplin, D D
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1991
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC52533/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1924307/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.19.8485
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