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Interleukin 1 is processed and released during apoptosis.

Interleukin (IL-) 1 alpha and 1 beta are synthesized as 31- to 34-kDa pro molecules. They are released from monocytes and macrophages as proteolytically processed 17-kDa mature molecules that bind with high affinity to specific receptors on target cells. IL-1 is not released via the classic secretor...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Hogquist, K A, Nett, M A, Unanue, E R, Chaplin, D D
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1991
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC52533/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1924307/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.19.8485
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