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Sema-1a reverse signaling promotes midline crossing in response to secreted Semaphorins

Commissural axons must cross the midline to form functional midline circuits. In the invertebrate nerve cord and vertebrate spinal cord, midline crossing is mediated in part by Netrin-dependent chemoattraction. Loss of crossing, however, is incomplete in mutants for Netrin or its receptor Frazzled/D...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Hernandez-Fleming, Melissa, Rohrbach, Ethan, Bashaw, Greg J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5253228/
https://ncbi.nlm.nih.gov/pubmed/28052247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.12.027
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