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Probing the Role of the Backbone Carbonyl Interaction with the Cu(A) Center in Azurin by Replacing the Peptide Bond with an Ester Linkage
The role of a backbone carbonyl interaction with an engineered Cu(A) center in azurin was investigated by developing a method of synthesis and incorporation of a depsipeptide where one of the amide bonds in azurin is replaced by an ester bond using expressed protein ligation. Studies by electronic a...
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| Pubblicato in: | Chem Commun (Camb) |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5253137/ https://ncbi.nlm.nih.gov/pubmed/27918029 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6cc07274g |
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