Two sites in the tissue factor extracellular domain mediate the recognition of the ligand factor VIIa.
Tissue factor (TF) binds the serine protease coagulation factor VIIa and initiates the coagulation protease cascade by forming a catalytic cofactor-enzyme complex. Using a photoactivatable crosslinking reagent coupled to factor VIIa, we have identified interactive sites in the amino-terminal (residu...
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| Yayımlandı: | Proc Natl Acad Sci U S A |
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| Asıl Yazarlar: | , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
National Academy of Sciences
1991
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC52522/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1924302/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.19.8430 |
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