Dual-Probe Assay for Rapid Detection of Drug-Resistant Mycobacterium tuberculosis by Real-Time PCR

Mutations in particular nucleotides of genes coding for drug targets or drug-converting enzymes lead to drug resistance in Mycobacterium tuberculosis. For rapid detection of drug-resistant M. tuberculosis in clinical specimens, a simple and applicable method is needed. Eight TaqMan minor groove bind...

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Main Authors: Wada, Takayuki, Maeda, Shinji, Tamaru, Aki, Imai, Shigeyoshi, Hase, Atsushi, Kobayashi, Kazuo
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2004
Assuntos:
Mycobacteriology and Aerobic Actinomycetes
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC525196/
https://ncbi.nlm.nih.gov/pubmed/15528726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.42.11.5277-5285.2004
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