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Structure and Polymorphism of the UL6 Portal Protein of Herpes Simplex Virus Type 1

By electron microscopy and image analysis, we find that baculovirus-expressed UL6 is polymorphic, consisting of rings of 11-, 12-, 13-, and 14-fold symmetry. The 12-mer is likely to be the oligomer incorporated into procapsids: at a resolution of 16 Å, it has an axial channel, peripheral flanges, an...

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Detalles Bibliográficos
Publicado en:J Virol
Principais autores: Trus, Benes L., Cheng, Naiqian, Newcomb, William W., Homa, Fred L., Brown, Jay C., Steven, Alasdair C.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 2004
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC525097/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15507654/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.78.22.12668-12671.2004
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