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Structure and Polymorphism of the UL6 Portal Protein of Herpes Simplex Virus Type 1

By electron microscopy and image analysis, we find that baculovirus-expressed UL6 is polymorphic, consisting of rings of 11-, 12-, 13-, and 14-fold symmetry. The 12-mer is likely to be the oligomer incorporated into procapsids: at a resolution of 16 Å, it has an axial channel, peripheral flanges, an...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Trus, Benes L., Cheng, Naiqian, Newcomb, William W., Homa, Fred L., Brown, Jay C., Steven, Alasdair C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2004
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC525097/
https://ncbi.nlm.nih.gov/pubmed/15507654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.22.12668-12671.2004
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