Transition from Acute to Persistent Theiler's Virus Infection Requires Active Viral Replication That Drives Proinflammatory Cytokine Expression and Chronic Demyelinating Disease

The dynamics of Theiler's murine encephalomyelitis virus (TMEV) RNA replication in the central nervous systems of susceptible and resistant strains of mice were examined by quantitative real-time reverse transcription-PCR and were found to correlate with host immune responses. During the acute phase...

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Pubblicato in:	J Virol
Autori principali:	Trottier, Mark, Schlitt, Brian P., Kung, Aisha Y., Lipton, Howard L.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2004
Soggetti:	Pathogenesis and Immunity
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC525090/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15507635/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.78.22.12480-12488.2004
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