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Transition from Acute to Persistent Theiler's Virus Infection Requires Active Viral Replication That Drives Proinflammatory Cytokine Expression and Chronic Demyelinating Disease

The dynamics of Theiler's murine encephalomyelitis virus (TMEV) RNA replication in the central nervous systems of susceptible and resistant strains of mice were examined by quantitative real-time reverse transcription-PCR and were found to correlate with host immune responses. During the acute...

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Bibliografiske detaljer
Main Authors: Trottier, Mark, Schlitt, Brian P., Kung, Aisha Y., Lipton, Howard L.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2004
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC525090/
https://ncbi.nlm.nih.gov/pubmed/15507635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.22.12480-12488.2004
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