The fate of BRCA1-related germline mutations in triple-negative breast tumors

The preservation of pathogenic BRCA1/2 germline mutations in tumor tissues is usually not questioned, while it remains unknown whether these interact with somatic genotypes for patient outcome. Herein we compared germline and tumor genotypes in operable triple-negative breast cancer (TNBC) and evalu...

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Publié dans:Am J Cancer Res
Auteurs principaux: Kotoula, Vassiliki, Fostira, Florentia, Papadopoulou, Kyriaki, Apostolou, Paraskevi, Tsolaki, Eleftheria, Lazaridis, Georgios, Manoussou, Kyriaki, Zagouri, Flora, Pectasides, Dimitrios, Vlachos, Ioannis, Tikas, Ioannis, Lakis, Sotiris, Konstantopoulou, Irene, Pentheroudakis, George, Gogas, Helen, Papakostas, Pavlos, Christodoulou, Christos, Bafaloukos, Dimitrios, Razis, Evangelia, Karavasilis, Vasilios, Bamias, Christina, Yannoukakos, Drakoulis, Fountzilas, George
Format: Artigo
Langue:Inglês
Publié: e-Century Publishing Corporation 2017
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Original Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5250684/
https://ncbi.nlm.nih.gov/pubmed/28123851
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