Tumor Infiltrating Lymphocytes Affect the Outcome of Patients with Operable Triple-Negative Breast Cancer in Combination with Mutated Amino Acid Classes

BACKGROUND: Stromal tumor infiltrating lymphocytes (TILs) density is an outcome predictor in triple-negative breast cancer (TNBC). Herein we asked whether TILs are related to coding mutation load and to the chemical class of the resulting mutated amino acids, i.e., charged, polar, and hydrophobic mu...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Kotoula, Vassiliki, Lakis, Sotiris, Vlachos, Ioannis S., Giannoulatou, Eleni, Zagouri, Flora, Alexopoulou, Zoi, Gogas, Helen, Pectasides, Dimitrios, Aravantinos, Gerasimos, Efstratiou, Ioannis, Pentheroudakis, George, Papadopoulou, Kyriaki, Chatzopoulos, Kyriakos, Papakostas, Pavlos, Sotiropoulou, Maria, Nicolaou, Irene, Razis, Evangelia, Psyrri, Amanda, Kosmidis, Paris, Papadimitriou, Christos, Fountzilas, George
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2016
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5042538/
https://ncbi.nlm.nih.gov/pubmed/27685159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0163138
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