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PI3K and MAPK pathways mediate the BDNF/TrkB-increased metastasis in neuroblastoma

Brain-derived neurotrophic factor (BDNF) and its tyrosine kinase receptor TrkB have been reported to be associated with poor prognosis in neuroblastoma (NB) patients. Our previous studies indicated that BDNF activation of TrkB induces chemo-resistance through activation of phosphoinositide-3-kinase...

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Detalhes bibliográficos
Publicado no:Tumour Biol
Main Authors: Hua, Zhongyan, Gu, Xiao, Dong, Yudi, Tan, Fei, Liu, Zhihui, Thiele, Carol J., Li, Zhijie
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5250655/
https://ncbi.nlm.nih.gov/pubmed/27752996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13277-016-5433-z
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