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Perforin and Fas Act Together in the Induction of Apoptosis, and Both Are Critical in the Clearance of Lymphocytic Choriomeningitis Virus Infection

In this report we questioned the current view that the two principal cytotoxic pathways, the exocytosis and the Fas ligand (FasL)/Fas-mediated pathway, have largely nonoverlapping biological roles. For this purpose we have analyzed the response of mice that lack Fas as well as granzyme A (gzmA) and...

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書誌詳細
主要な著者: Rode, Miriam, Balkow, Sandra, Sobek, Vera, Brehm, Reina, Martin, Praxedis, Kersten, Astrid, Dumrese, Tilman, Stehle, Thomas, Müllbacher, Arno, Wallich, Reinhard, Simon, Markus M.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2004
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC525048/
https://ncbi.nlm.nih.gov/pubmed/15507626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.22.12395-12405.2004
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