Altered Mineralization of Human Osteoarthritic Osteoblasts Is Attributable to Abnormal Type I Collagen Production

OBJECTIVE: Bone tissue in osteoarthritis (OA) is composed of abundant undermineralized osteoid matrix. The aim of this study was to investigate the mechanisms responsible for this abnormal matrix, using in vitro OA subchondral osteoblasts. METHODS: Primary normal and OA osteoblasts were prepared fro...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:Arthritis Rheum
Huvudupphovsmän: Couchourel, Denis, Aubry, Isabelle, Delalandre, Aline, Lavigne, Martin, Martel-Pelletier, Johanne, Pelletier, Jean-Pierre, Lajeunesse, Daniel
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2009
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5250342/
https://ncbi.nlm.nih.gov/pubmed/19404930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.24489
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk