Class II Integrase Mutants with Changes in Putative Nuclear Localization Signals Are Primarily Blocked at a Postnuclear Entry Step of Human Immunodeficiency Virus Type 1 Replication

Integrase has been implicated in human immunodeficiency virus type 1 (HIV-1) nuclear import. Integrase analyses, however, can be complicated by the pleiotropic nature of mutations: whereas class I mutants are integration defective, class II mutants display additional assembly and/or reverse transcri...

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הוצא לאור ב:	J Virol
Principais autores:	Lu, Richard, Limón, Ana, Devroe, Eric, Silver, Pamela A., Cherepanov, Peter, Engelman, Alan
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	American Society for Microbiology (ASM) 2004
נושאים:	Replication
גישה מקוונת:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC525011/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15542626/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.78.23.12735-12746.2004
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