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Lentiviral Vectors Interfering with Virus-Induced CD4 Down-Modulation Potently Block Human Immunodeficiency Virus Type 1 Replication in Primary Lymphocytes

CD4 down-modulation is essential for the production of human immunodeficiency virus (HIV) infectious particles. Disease progression correlates with enhanced viral induced CD4 down-modulation, and a subset of long-term nonprogressors carry viruses defective in this function. Despite multiple pieces o...

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Main Authors: Pham, Hang M., Argañaraz, Enrique R., Groschel, Bettina, Trono, Didier, Lama, Juan
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Microbiology 2004
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC524995/
https://ncbi.nlm.nih.gov/pubmed/15542659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.23.13072-13081.2004
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