Interferon Regulatory Factor 7 Is Associated with Epstein-Barr Virus-Transformed Central Nervous System Lymphoma and Has Oncogenic Properties

Interferon regulatory factor 7 (IRF-7) is implicated in the regulation of Epstein-Barr virus (EBV) latency. EBV transforms primary B cells, and the major EBV oncoprotein, latent membrane protein 1 (LMP-1), is required for the process. LMP-1 both induces the expression of IRF-7 and activates the IRF-...

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Autors principals: Zhang, Luwen, Zhang, Jun, Lambert, Que, Der, Channing J., Del Valle, Luis, Miklossy, Judith, Khalili, Kamel, Zhou, You, Pagano, Joseph S.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2004
Matèries:
Transformation and Oncogenesis
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC524977/
https://ncbi.nlm.nih.gov/pubmed/15542650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.23.12987-12995.2004
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