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Intracellular Signaling Molecules Activated by Epstein-Barr Virus for Induction of Interferon Regulatory Factor 7

Epstein-Barr virus (EBV) latent membrane protein 1 (LMP-1) is the principal oncogenic protein in the EBV transformation process. LMP-1 induces the expression of interferon regulatory factor 7 (IRF-7) and activates IRF-7 protein by phosphorylation and nuclear translocation. LMP-1 is an integral membr...

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Detalhes bibliográficos
Main Authors: Zhang, Luwen, Wu, Lihong, Hong, Ke, Pagano, Joseph S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC116135/
https://ncbi.nlm.nih.gov/pubmed/11711629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.24.12393-12401.2001
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