Cudraflavone C Induces Tumor-Specific Apoptosis in Colorectal Cancer Cells through Inhibition of the Phosphoinositide 3-Kinase (PI3K)-AKT Pathway

Cudraflavone C (Cud C) is a naturally-occurring flavonol with reported anti-proliferative activities. However, the mechanisms by which Cud C induced cytotoxicity have yet to be fully elucidated. Here, we investigated the effects of Cud C on cell proliferation, caspase activation andapoptosis inducti...

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Bibliographic Details
Published in:PLoS One
Main Authors: Soo, Hsien-Chuen, Chung, Felicia Fei-Lei, Lim, Kuan-Hon, Yap, Veronica Alicia, Bradshaw, Tracey D., Hii, Ling-Wei, Tan, Si-Hoey, See, Sze-Jia, Tan, Yuen-Fen, Leong, Chee-Onn, Mai, Chun-Wai
Format: Artigo
Language:Inglês
Published: Public Library of Science 2017
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5249192/
https://ncbi.nlm.nih.gov/pubmed/28107519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0170551
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