Dementia‐related adverse events in PARADIGM‐HF and other trials in heart failure with reduced ejection fraction

AIMS: Inhibition of neprilysin, an enzyme degrading natriuretic and other vasoactive peptides, is beneficial in heart failure with reduced ejection fraction (HFrEF), as shown in PARADIGM‐HF which compared the angiotensin receptor–neprilysin inhibitor (ARNI) sacubitril/valsartan with enalapril. As ne...

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Vydáno v:Eur J Heart Fail
Hlavní autoři: Cannon, Jane A., Shen, Li, Jhund, Pardeep S., Kristensen, Søren L., Køber, Lars, Chen, Fabian, Gong, Jianjian, Lefkowitz, Martin P., Rouleau, Jean L., Shi, Victor C., Swedberg, Karl, Zile, Michael R., Solomon, Scott D., Packer, Milton, McMurray, John J.V.
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley & Sons, Ltd 2016
Témata:
Medical Therapy
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5248626/
https://ncbi.nlm.nih.gov/pubmed/27868321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ejhf.687
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