Dementia‐related adverse events in PARADIGM‐HF and other trials in heart failure with reduced ejection fraction

AIMS: Inhibition of neprilysin, an enzyme degrading natriuretic and other vasoactive peptides, is beneficial in heart failure with reduced ejection fraction (HFrEF), as shown in PARADIGM‐HF which compared the angiotensin receptor–neprilysin inhibitor (ARNI) sacubitril/valsartan with enalapril. As ne...

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Detalhes bibliográficos
Publicado no:Eur J Heart Fail
Main Authors: Cannon, Jane A., Shen, Li, Jhund, Pardeep S., Kristensen, Søren L., Køber, Lars, Chen, Fabian, Gong, Jianjian, Lefkowitz, Martin P., Rouleau, Jean L., Shi, Victor C., Swedberg, Karl, Zile, Michael R., Solomon, Scott D., Packer, Milton, McMurray, John J.V.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Ltd 2016
Assuntos:
Medical Therapy
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5248626/
https://ncbi.nlm.nih.gov/pubmed/27868321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ejhf.687
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