Dementia‐related adverse events in PARADIGM‐HF and other trials in heart failure with reduced ejection fraction

AIMS: Inhibition of neprilysin, an enzyme degrading natriuretic and other vasoactive peptides, is beneficial in heart failure with reduced ejection fraction (HFrEF), as shown in PARADIGM‐HF which compared the angiotensin receptor–neprilysin inhibitor (ARNI) sacubitril/valsartan with enalapril. As ne...

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Dettagli Bibliografici
Pubblicato in:Eur J Heart Fail
Autori principali: Cannon, Jane A., Shen, Li, Jhund, Pardeep S., Kristensen, Søren L., Køber, Lars, Chen, Fabian, Gong, Jianjian, Lefkowitz, Martin P., Rouleau, Jean L., Shi, Victor C., Swedberg, Karl, Zile, Michael R., Solomon, Scott D., Packer, Milton, McMurray, John J.V.
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley & Sons, Ltd 2016
Soggetti:
Medical Therapy
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5248626/
https://ncbi.nlm.nih.gov/pubmed/27868321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ejhf.687
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