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TIM-1 defines a human regulatory B cell population that is altered in frequency and function in systemic sclerosis patients

BACKGROUND: Systemic sclerosis (SSc) is a systemic autoimmune disease characterized by excessive production of extracellular matrix by fibroblasts on skin and internal organs. Although Th2 cells have been involved in fibroblast stimulation, hyperactivated B cells may also play an important role. Reg...

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Detalhes bibliográficos
Publicado no:Arthritis Res Ther
Main Authors: Aravena, Octavio, Ferrier, Ashley, Menon, Madhvi, Mauri, Claudia, Aguillón, Juan Carlos, Soto, Lilian, Catalán, Diego
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5248463/
https://ncbi.nlm.nih.gov/pubmed/28103916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-016-1213-9
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