A High-affinity Interaction with ADP-Actin Monomers Underlies the Mechanism and In Vivo Function of Srv2/cyclase-associated Protein

Cyclase-associated protein (CAP), also called Srv2 in Saccharomyces cerevisiae, is a conserved actin monomer-binding protein that promotes cofilin-dependent actin turnover in vitro and in vivo. However, little is known about the mechanism underlying this function. Here, we show that S. cerevisiae CA...

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Main Authors: Mattila, Pieta K., Quintero-Monzon, Omar, Kugler, Jamie, Moseley, James B., Almo, Steven C., Lappalainen, Pekka, Goode, Bruce L.
格式: Artigo
語言:Inglês
出版: The American Society for Cell Biology 2004
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Articles
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC524793/
https://ncbi.nlm.nih.gov/pubmed/15356265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E04-06-0444
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