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A central role for the WH2 domain of Srv2/CAP in recharging actin monomers to drive actin turnover in vitro and in vivo

Cellular processes propelled by actin polymerization require rapid disassembly of filaments, and then efficient recycling of ADF/cofilin-bound ADP-actin monomers back to an assembly-competent ATP-bound state. How monomer recharging is regulated in vivo is still not well understood, but recent work s...

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Autori principali: Chaudhry, Faisal, Little, Kristin, Talarico, Lou, Quintero-Monzon, Omar, Goode, Bruce L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2857556/
https://ncbi.nlm.nih.gov/pubmed/20169536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cm.20429
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