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A central role for the WH2 domain of Srv2/CAP in recharging actin monomers to drive actin turnover in vitro and in vivo

Cellular processes propelled by actin polymerization require rapid disassembly of filaments, and then efficient recycling of ADF/cofilin-bound ADP-actin monomers back to an assembly-competent ATP-bound state. How monomer recharging is regulated in vivo is still not well understood, but recent work s...

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Detalhes bibliográficos
Main Authors: Chaudhry, Faisal, Little, Kristin, Talarico, Lou, Quintero-Monzon, Omar, Goode, Bruce L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2857556/
https://ncbi.nlm.nih.gov/pubmed/20169536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cm.20429
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