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Srv2/cyclase-associated protein forms hexameric shurikens that directly catalyze actin filament severing by cofilin

Actin filament severing is critical for the dynamic turnover of cellular actin networks. Cofilin severs filaments, but additional factors may be required to increase severing efficiency in vivo. Srv2/cyclase-associated protein (CAP) is a widely expressed protein with a role in binding and recycling...

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Detalhes bibliográficos
Main Authors: Chaudhry, Faisal, Breitsprecher, Dennis, Little, Kristin, Sharov, Grigory, Sokolova, Olga, Goode, Bruce L.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3530777/
https://ncbi.nlm.nih.gov/pubmed/23135996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E12-08-0589
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