Improved Affinity of a Human Anti-Entamoeba histolytica Gal/GalNAc Lectin Fab Fragment by a Single Amino Acid Modification of the Light Chain

We previously produced, in Escherichia coli, a human monoclonal antibody Fab fragment, CP33, specific for the galactose- and N-acetyl-d-galactosamine-inhibitable lectin of Entamoeba histolytica. To prepare antibodies with a higher affinity to the lectin, recombination PCR was used to exchange Ser(91...

Täydet tiedot

Bibliografiset tiedot

Julkaisussa:	Clin Diagn Lab Immunol
Päätekijät:	Tachibana, Hiroshi, Matsumoto, Naohisa, Cheng, Xun-Jia, Tsukamoto, Hideo, Yoshihara, Eisaku
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	American Society for Microbiology (ASM) 2004
Aiheet:	Antibodies and Mediators of Immunity
Linkit:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC524788/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15539510/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/CDLI.11.6.1085-1088.2004
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