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Perinatal Choline Supplementation Reduces Amyloidosis and Increases Choline Acetyltransferase Expression in the Hippocampus of the APPswePS1dE9 Alzheimer's Disease Model Mice

Prevention of Alzheimer's disease (AD) is a major goal of biomedical sciences. In previous studies we showed that high intake of the essential nutrient, choline, during gestation prevented age-related memory decline in a rat model. In this study we investigated the effects of a similar treatmen...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Mellott, Tiffany J., Huleatt, Olivia M., Shade, Bethany N., Pender, Sarah M., Liu, Yi B., Slack, Barbara E., Blusztajn, Jan K.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5245895/
https://ncbi.nlm.nih.gov/pubmed/28103298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0170450
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