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Expression of human factor IX in rat capillary endothelial cells: toward somatic gene therapy for hemophilia B.

In aiming to develop a gene therapy approach for hemophilia B, we expressed and characterized human factor IX in rat capillary endothelial cells (CECs). Moloney murine leukemia virus-derived retrovirus vectors that contain human factor IX cDNA linked to heterologous promoters and the neomycin-resist...

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Detalhes bibliográficos
Main Authors: Yao, S N, Wilson, J M, Nabel, E G, Kurachi, S, Hachiya, H L, Kurachi, K
Formato: Artigo
Idioma:Inglês
Publicado em: 1991
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC52454/
https://ncbi.nlm.nih.gov/pubmed/1896457
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