Expression of human factor IX in rat capillary endothelial cells: toward somatic gene therapy for hemophilia B.

In aiming to develop a gene therapy approach for hemophilia B, we expressed and characterized human factor IX in rat capillary endothelial cells (CECs). Moloney murine leukemia virus-derived retrovirus vectors that contain human factor IX cDNA linked to heterologous promoters and the neomycin-resist...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Yao, S N, Wilson, J M, Nabel, E G, Kurachi, S, Hachiya, H L, Kurachi, K
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1991
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC52454/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1896457/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.18.8101
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