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Immune-enrichment of insulin in bio-fluids on gold-nanoparticle decorated target plate and in situ detection by MALDI MS

BACKGROUND: Detection of low-abundance biomarkers using mass spectrometry (MS) is often hampered by non-target molecules in biological fluids. In addition, current procedures for sample preparation increase sample consumption and limit analysis throughput. Here, a simple strategy is proposed to cons...

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Detalhes bibliográficos
Publicado no:Clin Proteomics
Main Authors: Liang, Kai, Wu, Hongmei, Li, Yan
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5244591/
https://ncbi.nlm.nih.gov/pubmed/28115918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12014-017-9139-z
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